Products
TRIM21 antibody
- Product Name
- TRIM21 antibody
- Catalogue No.
- FNab08972
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- tripartite motif-containing 21
- Alternative Names
- 52 kDa Ro protein antibody, RING finger protein 81 antibody, RNF81 antibody, Ro(SS A) antibody, RO52 antibody, SS A antibody, SSA antibody, SSA1 antibody, TRIM21 antibody, tripartite motif containing 21 antibody
- UniProt ID
- P19474
- Observed MW
- 54 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
A549 cells were subjected to SDS PAGE followed by western blot with FNab08972(TRIM21 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab08972(TRIM21 antibody) at dilution of 1:50
- Background
- This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
