Products

TRAF4 antibody

Synonyms:CART1 antibody, MLN62 antibody, RNF83 antibody
Catalogue No.:FNab08919Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
TRAF4 antibody
Catalogue No.
FNab08919
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
TNF receptor-associated factor 4
Alternative Names
CART1 antibody, MLN62 antibody, RNF83 antibody
UniProt ID
Q9BUZ4
Observed MW
54 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab08919(TRAF4 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab08919(TRAF4 antibody) at dilution of 1:50
Immunofluorescence analysis of A549 cells using FNab08919(TRAF4 antibody).
Background
This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.