Products
TRAF3 antibody
- Product Name
- TRAF3 antibody
- Catalogue No.
- FNab08917
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- TNF receptor-associated factor 3
- Alternative Names
- CAP 1 antibody, CAP1 antibody, CD40 binding protein antibody, CD40bp antibody, CRAF1 antibody, LAP1 antibody, LMP1 associated protein 1 antibody, TRAF3 antibody
- UniProt ID
- Q13114
- Observed MW
- 70 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200 - 1:1000; IHC: 1:50 - 1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08917( TRAF3 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab08917( TRAF3 Antibody) at dilution of 1:100
- Background
- The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.
