mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab08889(TPM2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab08889(TPM2 antibody) at dilution of 1:50
Background
This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.