TOP1 antibody

Synonyms:DNA topoisomerase 1 antibody, DNA topoisomerase I antibody, TOP1 antibody, TOPI antibody, Top-I antibody, topoisomerase (DNA) I antibody
Catalogue No.:FNab08865Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
TOP1 antibody
Catalogue No.
FNab08865
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
topoisomerase (DNA) I
Alternative Names
DNA topoisomerase 1 antibody, DNA topoisomerase I antibody, TOP1 antibody, TOPI antibody, Top-I antibody, topoisomerase (DNA) I antibody
UniProt ID
P11387
Observed MW
100 kDa
Application
Tested Applications
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:100
Validated Images
L02 cells were subjected to SDS PAGE followed by western blot with FNab08865(TOP1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human cervical cancer using FNab08865(TOP1 antibody) at dilution of 1:50
Background
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.