Products

TNNC1 antibody

Synonyms:TNNC antibody
Catalogue No.:FNab08835Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
TNNC1 antibody
Catalogue No.
FNab08835
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
troponin C type 1 (slow)
Alternative Names
TNNC antibody
UniProt ID
P63316
Observed MW
18 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab08835( TNNC1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon carcinoma using FNab08835(TNNC1 antibody) at dilution of 1:50
Background
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.