Products
TNF alpha antibody
- Product Name
- TNF alpha antibody
- Catalogue No.
- FNab09822
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- tumor necrosis factor (TNF superfamily, member 2)
- Alternative Names
- Cachectin antibody, DIF antibody, TNF antibody, TNF a antibody, TNF alpha antibody, TNFA antibody, TNF-a antibody, TNFSF2 antibody, Tumor necrosis factor antibody
- UniProt ID
- P01375
- Observed MW
- 21 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:1000 - 1:2000; IHC: 1:50 - 1:100
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab09822( TNF-a Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach tissue slide using FNab09822( TNF-a Antibody) at dilution of 1:100.
- Background
- This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
