Products
TMEM173 antibody
- Product Name
- TMEM173 antibody
- Catalogue No.
- FNab08759
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- transmembrane protein 173
- Alternative Names
- ERIS antibody, hMITA antibody, hSTING antibody, MITA antibody, MPYS antibody, NET23 antibody, SAVI antibody, STING antibody
- UniProt ID
- Q86WV6
- Observed MW
- 39 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab08759(TMEM173 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human spleen using FNab08759(TMEM173 antibody) at dilution of 1:100
- Background
- This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
