Products
TLR4 antibody
- Product Name
- TLR4 antibody
- Catalogue No.
- FNab09837
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG2b
- Clone ID
- 3E7
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- toll-like receptor 4
- Alternative Names
- ARMD10 antibody, CD284 antibody, hToll antibody, TLR4 antibody, TOLL antibody, toll like receptor 4 antibody
- UniProt ID
- O00206
- Observed MW
- 100 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:1000-1:8000; IHC: 1:50-1:500
Validated Images
RAW 264.7 cells were subjected to SDS PAGE followed by western blot with FNab09837( TLR4 Antibody) at dilution of 1:4000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab09837( TLR4 Antibody) at dilution of 1:200
- Background
- TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
