Products
TIPIN antibody
- Product Name
- TIPIN antibody
- Catalogue No.
- FNab08716
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- TIMELESS interacting protein
- Alternative Names
- TIPIN antibody, FLJ20516 antibody, TIMELESS interacting protein antibody
- UniProt ID
- Q9BVW5
- Observed MW
- 48kd
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:200-1:2000
Validated Images
TIPIN transfected 293T cells were subjected to SDS PAGE followed by western blot with FNab08716(TIPIN antibody) at dilution of 1:500
- Background
- Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress.
