Products
TIA1 antibody
- Product Name
- TIA1 antibody
- Catalogue No.
- FNab08685
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- TIA1 cytotoxic granule-associated RNA binding protein
- UniProt ID
- P31483
- Observed MW
- 54 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:20 - 1:100
Validated Images
BT-474 cells were subjected to SDS PAGE followed by western blot with FNab08685(TIA1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab08685(TIA1 antibody) at dilution of 1:100
- Background
- The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
