HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08614(TFAM antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney slide using FNab08614( TFAM Antibody) at dilution of 1:50
Background
This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants.