Products

TBXAS1 antibody

Synonyms:CYP5 antibody, CYP5A1 antibody
Catalogue No.:FNab08543Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
TBXAS1 antibody
Catalogue No.
FNab08543
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
thromboxane A synthase 1 (platelet)
Alternative Names
CYP5 antibody, CYP5A1 antibody
UniProt ID
P24557
Observed MW
60 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
A549 cells were subjected to SDS PAGE followed by western blot with FNab08543(TBXAS1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab08543(TBXAS1 antibody) at dilution of 1:50
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.