Products
TAX1BP1 antibody
- Product Name
- TAX1BP1 antibody
- Catalogue No.
- FNab08506
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Tax1(human T-cell leukemia virus type I) binding protein 1
- Alternative Names
- CALCOCO3 antibody, T6BP antibody, Tax1 binding protein 1 antibody, TAX1BP1 antibody, TRAF6 binding protein antibody, TXBP151 antibody
- UniProt ID
- Q86VP1
- Observed MW
- 68 kDa, 85 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08506(TAX1BP1 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded rat kidney tissue slide using FNab08506( TAX1BP1 Antibody) at dilution of 1:100
- Background
- TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms with MW 65-68 kDa and 86-91 kDa.
