Hela cells were subjected to SDS PAGE followed by western blot with FNab09979(TAB2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human intestinal cancer using FNab09979(TAB2 antibody) at dilution of 1:100
Background
Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.