Products
SURF1 antibody
- Product Name
- SURF1 antibody
- Catalogue No.
- FNab08399
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- surfeit 1
- Alternative Names
- SURF-1 antibody
- UniProt ID
- Q15526
- Observed MW
- 33 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
human heart tissue were subjected to SDS PAGE followed by western blot with FNab08399(SURF1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human heart using FNab08399(SURF1 antibody) at dilution of 1:50
- Background
- This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
