Products
STK4 antibody
- Product Name
- STK4 antibody
- Catalogue No.
- FNab08339
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- serine/threonine kinase 4
- Alternative Names
- DKFZp686A2068 antibody, KRS2 antibody, MST 1 antibody, MST1 antibody, serine/threonine kinase 4 antibody, STE20 like kinase MST1 antibody, STK4 antibody, YSK3 antibody
- UniProt ID
- Q13043
- Observed MW
- 56 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP : 1:20 - 1:50
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab08339(STK4 antibody) at dilution of 1:1000
IP Result of anti-STK4/MST1 (IP:FNab08339, 4ug; Detection:FNab08339 1:1000) with HeLa cells lysate 1200ug.
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab08339(STK4 antibody) at dilution of 1:50
- Background
- The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
