Products
SSRP1 antibody
- Product Name
- SSRP1 antibody
- Catalogue No.
- FNab08250
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- structure specific recognition protein 1
- Alternative Names
- FACT80 antibody
- UniProt ID
- Q08945
- Observed MW
- Refer to figures
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab08250(SSRP1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse liver using FNab08250(SSRP1 antibody) at dilution of 1:100
- Background
- The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
