Products
SSB antibody
- Product Name
- SSB antibody
- Catalogue No.
- FNab08246
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Sjogren syndrome antigen B (autoantigen La)
- UniProt ID
- P05455
- Observed MW
- 47 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:1000; IHC: 1:100 - 1:200
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08246( SSB Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab08246(SSB antibody) at dilution of 1:50
- Background
- The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.
