Products
SPTLC1 antibody
- Product Name
- SPTLC1 antibody
- Catalogue No.
- FNab08206
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- serine palmitoyltransferase, long chain base subunit 1
- Alternative Names
- HSAN antibody, HSAN1 antibody, HSN1 antibody, LBC1 antibody, LCB 1 antibody, LCB1 antibody, Serine palmitoyltransferase 1 antibody, SPT 1 antibody, SPT1 antibody, SPTI antibody, SPTLC1 antibody
- UniProt ID
- O15269
- Observed MW
- 53 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab08206(SPTLC1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney using FNab08206(SPTLC1 antibody) at dilution of 1:100
- Background
- This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.
