SPARC antibody

Synonyms:ON antibody
Catalogue No.:FNab08153Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SPARC antibody
Catalogue No.
FNab08153
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
secreted protein, acidic, cysteine-rich (osteonectin)
Alternative Names
ON antibody
UniProt ID
P09486
Observed MW
35 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
human placenta tissue were subjected to SDS PAGE followed by western blot with FNab08153(SPARC antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab08153(SPARC antibody) at dilution of 1:100
Background
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.