SOD1 antibody

Synonyms:Superoxide dismutase [Cu-Zn] antibody, Superoxide dismutase 1 antibody, hSod1 antibody
Catalogue No.:FNab08103Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IP, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SOD1 antibody
Catalogue No.
FNab08103
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
superoxide dismutase 1, soluble
Alternative Names
Superoxide dismutase [Cu-Zn] antibody, Superoxide dismutase 1 antibody, hSod1 antibody
UniProt ID
P00441
Observed MW
16 kDa
Application
Tested Applications
ELISA, WB, IHC, IP, IF
Recommended dilution
WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:100-1:400; IF: 1:10-1:100
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08103(SOD1 antibody) at dilution of 1:1500
IP Result of anti-SOD1 (IP:FNab08103, 3ug; Detection:FNab08103 1:1500) with HEK-293 cells lysate 1000ug.
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab08103(SOD1 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Background
Superoxide dismutase 1, soluble(amyotrophic lateral sclerosis 1(adult))(SOD1, synonyms: ALS, SOD, ALS1, IPOA) binds copper and zinc ions and is one of two isozymes responsible for destroying free uperoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.