Products
SNX17 antibody
- Product Name
- SNX17 antibody
- Catalogue No.
- FNab08084
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- sorting nexin 17
- Alternative Names
- KIAA0064 antibody
- UniProt ID
- Q15036
- Observed MW
- 52 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08084(SNX17 antibody) at dilution of 1:500
IP Result of anti-SNX17 (IP:FNab08084, 4ug; Detection:FNab08084 1:1000) with HeLa cells lysate 1200ug.
Immunohistochemistry of paraffin-embedded human colon tissue slide using FNab08084(SNX17 Antibody) at dilution of 1:50
Immnuofluorescent analysis of HepG2 cells using FNab08084(SNX17 Antibody) at dilution of 1:50
- Background
- Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate(PtdIns(3P)).
