K-562 cells were subjected to SDS PAGE followed by western blot with FNab08009(SMARCC1 antibody) at dilution of 1:1000
IP Result of anti-SMARCC1 (IP:FNab08009, 4ug; Detection:FNab08009 1:600) with mouse brain tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human kidney cancer using FNab08009(SMARCC1 antibody) at dilution of 1:100
Background
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.