SIRT3 antibody

Synonyms:hSIRT3 antibody, SIR2 like protein 3 antibody, SIR2L3 antibody, SIRT3 antibody
Catalogue No.:FNab07881Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SIRT3 antibody
Catalogue No.
FNab07881
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
sirtuin (silent mating type information regulation 2 homolog) 3
Alternative Names
hSIRT3 antibody, SIR2 like protein 3 antibody, SIR2L3 antibody, SIRT3 antibody
UniProt ID
Q9NTG7
Observed MW
44 kDa, 27 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100
Validated Images
SW620 cells were subjected to SDS PAGE followed by western blot with FNab07881(SIRT3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney tissue slide using FNab07881( SIRT3 Antibody) at dilution of 1:100
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.