SHMT2 antibody

Synonyms:GLYA antibody, HEL-S-51e antibody, SHMT antibody
Catalogue No.:FNab07851Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SHMT2 antibody
Catalogue No.
FNab07851
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
serine hydroxymethyltransferase 2 (mitochondrial)
Alternative Names
GLYA antibody, HEL-S-51e antibody, SHMT antibody
UniProt ID
P34897
Observed MW
55 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab07851(SHMT2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney using FNab07851(SHMT2 antibody) at dilution of 1:100
Background
This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5, 10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.