Products

SEPT7 antibody

Synonyms:CDC10 antibody, CDC10 protein homolog antibody, CDC3 antibody, Nbla02942 antibody, SEPT7 antibody, SEPT7A antibody, septin 7 antibody
Catalogue No.:FNab07726Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, IF, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SEPT7 antibody
Catalogue No.
FNab07726
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
septin 7
Alternative Names
CDC10 antibody, CDC10 protein homolog antibody, CDC3 antibody, Nbla02942 antibody, SEPT7 antibody, SEPT7A antibody, septin 7 antibody
UniProt ID
Q16181
Observed MW
51 kDa
Application
Tested Applications
ELISA, IHC, IF, WB
Recommended dilution
WB: 1:1000 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab07726(SEPT7 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab07726(SEPT7 antibody) at dilution of 1:100
Immunofluorescence analysis of HeLa cells using FNab07726(SEPT7 antibody).
Background
This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.