Products
SECISBP2 antibody
- Product Name
- SECISBP2 antibody
- Catalogue No.
- FNab07695
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- SECIS binding protein 2
- Alternative Names
- SBP2 antibody
- UniProt ID
- Q96T21
- Observed MW
- 110 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab07595(SECISBP2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver injury using FNab07695(SECISBP2 antibody) at dilution of 1:100
- Background
- The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.
