Products
SAP18 antibody
- Product Name
- SAP18 antibody
- Catalogue No.
- FNab07596
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Sin3A-associated protein, 18kDa
- UniProt ID
- O00422
- Observed MW
- 18 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200 - 1:2000; IHC: 1:50 - 1:200
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab07596(SAP18 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab07596(SAP18 antibody) at dilution of 1:50
- Background
- Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.
