Products
RECK antibody
- Product Name
- RECK antibody
- Catalogue No.
- FNab10074
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- reversion-inducing-cysteine-rich protein with kazal motifs
- Alternative Names
- RECK antibody, ST15 antibody, reversion-inducing cysteine-rich protein with Kazal motifs antibody
- UniProt ID
- O95980
- Observed MW
- 110 kDa
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:20-1:200
Validated Images
Immunohistochemistry of paraffin-embedded human kidney using FNab10074( RECK Antibody) at dilution of 1:100
- Background
- Negatively regulates matrix metalloproteinase-9(MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
