Products
RbAp46 antibody
- Product Name
- RbAp46 antibody
- Catalogue No.
- FNab07147
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- retinoblastoma binding protein 7
- Alternative Names
- Histone binding protein RBBP7 antibody, RbAp46 antibody, RBBP 7 antibody, RBBP7 antibody
- UniProt ID
- Q16576
- Observed MW
- 48 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; ChIP: 1:50 - 1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab07147(RBBP7 antibody) at dilution of 1:1000
IP Result of anti-RbAp46 (IP:FNab07147, 4ug; Detection:FNab07147 1:300) with A431 cells lysate 2400ug.
Immunohistochemistry of paraffin-embedded human gastric cancer using FNab07147(RBBP7 antibody) at dilution of 1:50
- Background
- This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
