HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab06968( PYCR1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab06968( PYCR1 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Background
This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants.