Products

PUF60 antibody

Synonyms:FIR antibody, ROBPI antibody, SIAHBP1 antibody
Catalogue No.:FNab06954Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PUF60 antibody
Catalogue No.
FNab06954
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
poly-U binding splicing factor 60KDa
Alternative Names
FIR antibody, ROBPI antibody, SIAHBP1 antibody
UniProt ID
Q9UHX1
Observed MW
65 kDa
Application
Tested Applications
ELISA, WB, IHC, IF, IP
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100; IP: 1:20 - 1:50
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06954(PUF60 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human well-differentiated squamous skin carcinoma using FNab06954(PUF60 antibody) at dilution of 1:100
Background
This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.