human placenta tissue were subjected to SDS PAGE followed by western blot with FNab06693(PPOX antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver injury using FNab06693(PPOX antibody) at dilution of 1:100
Background
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.