PPAN antibody

Synonyms:BXDC3 antibody, SSF1 antibody
Catalogue No.:FNab06658Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, IHC, WB, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PPAN antibody
Catalogue No.
FNab06658
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
peter pan homolog (Drosophila)
Alternative Names
BXDC3 antibody, SSF1 antibody
UniProt ID
Q9NQ55
Observed MW
55 kDa
Application
Tested Applications
ELISA, IHC, WB, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab06658(PPAN antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate using FNab06658(PPAN antibody) at dilution of 1:50
Background
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.