anti- POLR1A antibody

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Product Information
Product name

anti- POLR1A antibody

Alternative name

POLR1A Antibody

Catalogue No.

FNab06615

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Description

POLR1A antibody: Rabbit Polyclonal antibody to POLR1A

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Background

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition (By similarity) .

Immunogen Information
Immunogen

polymerase (RNA) I polypeptide A, 194kDa

Application
Specificity

Human

Tested Application

ELISA, WB

Uniprot information
Gene Name

POLR1A

Uniprot ID

O95602

RetailerEnd User





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Hotline

027-87384275
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