COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab06611( POLG2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab06611(POLG2 antibody) at dilution of 1:100
Background
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.