POLG2 antibody

Synonyms:MTPOLB antibody
Catalogue No.:FNab06611Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, WB, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
POLG2 antibody
Catalogue No.
FNab06611
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
polymerase (DNA directed), gamma 2, accessory subunit
Alternative Names
MTPOLB antibody
UniProt ID
Q9UHN1
Observed MW
55 kDa
Application
Tested Applications
ELISA, IHC, WB, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab06611( POLG2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab06611(POLG2 antibody) at dilution of 1:100
Background
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.