HeLa cells were subjected to SDS PAGE followed by western blot with FNab06606(POLD1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human heart using FNab06606(POLD1 antibody) at dilution of 1:50
Immunofluorescence analysis of U2OS cells using FNab06606(POLD1 antibody) at dilution of 1:50
Background
This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.