HeLa cells were subjected to SDS PAGE followed by western blot with FNab06390(PHIP antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney cancer using FNab06390(PHIP antibody) at dilution of 1:100
Background
This gene encodes a protein that binds to the insulin receptor substrate 1 protein and regulates glucose transporter translocation in skeletal muscle cells. The encoded protein may also regulate growth and survival of pancreatic beta cells. Elevated copy number of this gene may be associated with melanoma severity and the encoded protein may promote melanoma metastasis in human patients.