PFKM antibody

Synonyms:GSD7 antibody, PFK 1 antibody, PFK A antibody, PFK M antibody, PFKM antibody, PFKX antibody, Phosphofructokinase 1 antibody, Phosphofructokinase M antibody, phosphofructokinase antibody, muscle antibody, Phosphohexokinase antibody
Catalogue No.:FNab06341Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PFKM antibody
Catalogue No.
FNab06341
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
phosphofructokinase, muscle
Alternative Names
GSD7 antibody, PFK 1 antibody, PFK A antibody, PFK M antibody, PFKM antibody, PFKX antibody, Phosphofructokinase 1 antibody, Phosphofructokinase M antibody, phosphofructokinase antibody, muscle antibody, Phosphohexokinase antibody
UniProt ID
P08237
Observed MW
85 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab06341(PFKM antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human esophageal cancer using FNab06341(PFKM Antibody) at dilution of 1:100
Background
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.