Products

PEX19 antibody

Synonyms:33 kDa housekeeping protein antibody, D1S2223E antibody, HK33 antibody, Peroxin 19 antibody, PEX19 antibody, PMP1 antibody, PMPI antibody, PXF antibody, PXMP1 antibody
Catalogue No.:FNab06329Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PEX19 antibody
Catalogue No.
FNab06329
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
peroxisomal biogenesis factor 19
Alternative Names
33 kDa housekeeping protein antibody, D1S2223E antibody, HK33 antibody, Peroxin 19 antibody, PEX19 antibody, PMP1 antibody, PMPI antibody, PXF antibody, PXMP1 antibody
UniProt ID
P40855
Observed MW
37 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
human heart tissue were subjected to SDS PAGE followed by western blot with FNab06329(PEX19 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human gliomas using FNab06329(PEX19 antibody) at dilution of 1:100
Background
This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.