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PEX19 antibody
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Synonyms: | 33 kDa housekeeping protein antibody, D1S2223E antibody, HK33 antibody, Peroxin 19 antibody, PEX19 antibody, PMP1 antibody, PMPI antibody, PXF antibody, PXMP1 antibody | ||
Catalogue No.: | FNab06329 | Reativity: | Human, Mouse |
Host: | Rabbit | Tested Application: | ELISA, WB, IHC |
Clonality: | polyclonal | Isotype: | IgG |
- SPECIFICATIONS
- Product Name
- PEX19 antibody
- Catalogue No.
- FNab06329
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- peroxisomal biogenesis factor 19
- Alternative Names
- 33 kDa housekeeping protein antibody, D1S2223E antibody, HK33 antibody, Peroxin 19 antibody, PEX19 antibody, PMP1 antibody, PMPI antibody, PXF antibody, PXMP1 antibody
- UniProt ID
- P40855
- Observed MW
- 37 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
human heart tissue were subjected to SDS PAGE followed by western blot with FNab06329(PEX19 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human gliomas using FNab06329(PEX19 antibody) at dilution of 1:100
- Background
- This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.