Products

Peroxiredoxin 3 antibody

Synonyms:Antioxidant protein 1 antibody, AOP 1 antibody, AOP1 antibody, HBC189 antibody, MER5 antibody, Peroxiredoxin 3 antibody, Peroxiredoxin III antibody, PRDX3 antibody, PRO1748 antibody, Protein MER5 homolog antibody, Prx III antibody, PRX3 antibody, SP 22 antibody
Catalogue No.:FNab06322Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Peroxiredoxin 3 antibody
Catalogue No.
FNab06322
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
peroxiredoxin 3
Alternative Names
Antioxidant protein 1 antibody, AOP 1 antibody, AOP1 antibody, HBC189 antibody, MER5 antibody, Peroxiredoxin 3 antibody, Peroxiredoxin III antibody, PRDX3 antibody, PRO1748 antibody, Protein MER5 homolog antibody, Prx III antibody, PRX3 antibody, SP 22 antibody
UniProt ID
P30048
Observed MW
25 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06322(Prx III antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab06322( Prx III Antibody) at dilution of 1:50
Immunofluorescence analysis of HeLa cells using FNab06322( Prx III Antibody). Blue: DAPI for nuclear staining.
Background
This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.