A549 cells were subjected to SDS PAGE followed by western blot with FNab06265(PDGFD antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human prostate cancer using FNab06265(PDGFD antibody) at dilution of 1:100
Background
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix(By similarity).