PDCD6 antibody

Synonyms:ALG2 antibody
Catalogue No.:FNab06242Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PDCD6 antibody
Catalogue No.
FNab06242
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
programmed cell death 6
Alternative Names
ALG2 antibody
UniProt ID
O75340
Observed MW
16 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:200 - 1:2000; IHC: 1:50 - 1:200
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab06242(PDCD6 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach cancer using FNab06242(PDCD6 antibody) at dilution of 1:100
Background
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.