Products
PCNA antibody
- Product Name
- PCNA antibody
- Catalogue No.
- FNab06215
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- proliferating cell nuclear antigen
- Alternative Names
- Proliferating cell nuclear antigen antibody, Cyclin antibody
- UniProt ID
- P12004
- Observed MW
- 38 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab06215(PCNA antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach cancer using FNab06215(PCNA antibody) at dilution of 1:50
- Background
- The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
