Products
PARP1 antibody
- Product Name
- PARP1 antibody
- Catalogue No.
- FNab06151
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- poly (ADP-ribose) polymerase 1
- Alternative Names
- ADPRT antibody, ADPRT 1 antibody, ADPRT1 antibody, pADPRT 1 antibody, PARP antibody, PARP 1 antibody, PARP1 antibody, poly (ADP ribose) polymerase 1 antibody, Poly [ADP ribose] polymerase 1 antibody, Poly[ADP ribose] synthase 1 antibody, PPOL antibody
- UniProt ID
- P09874
- Observed MW
- 115 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06151(PARP1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab06151(PARP1 antibody) at dilution of 1:100
- Background
- This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
