Products
P62/SQSTM1 antibody
- Product Name
- P62/SQSTM1 antibody
- Catalogue No.
- FNab06086
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- sequestosome 1
- Alternative Names
- P62 antibody, sequestosome 1 antibody, SQSTM1 antibody, Ubiquitin binding protein p62 antibody
- UniProt ID
- Q13501
- Observed MW
- 65 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:20 - 1:100
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06086(SQSTM1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab06086( P62 SQSTM1 Antibody) at dilution of 1:50
Immunofluorescent analysis of ( -20℃ Ethanol ) fixed Starvation treated HepG2 cells using FNab06086(SQSTM1 Antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
