Products
P62/SQSTM1 antibody
- Product Name
- P62/SQSTM1 antibody
- Catalogue No.
- FNab06087
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- sequestosome 1
- Alternative Names
- P62 antibody, sequestosome 1 antibody, SQSTM1 antibody, Ubiquitin binding protein p62 antibody
- UniProt ID
- Q13501
- Observed MW
- 62 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; IP: 1:20 - 1:50
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06087(SQSTM1 antibody) at dilution of 1:1000
IP result of anti-P62/SQSTM1(IP:FNab06087, 4ug; Detection:FNab06087 1:1000) with HEK-293 cells lysate 4000 ug
Immunohistochemistry of paraffin-embedded human esophagus using FNab06087(SQSTM1 antibody) at dilution of 1:50
- Background
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
