anti- P16-INK4A antibody

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Product Information
Product name

anti- P16-INK4A antibody

Alternative name

ARF antibody, CDKN2A antibody, CDK4 inhibitor p16 INK4 antibody, CDK4 inhibitor p16INK4 antibody, CDK4I antibody, CDKN2 antibody, CDKN2A antibody, CMM2 antibody, INK4 antibody, INK4a antibody, MLM antibody, MTS 1 antibody, MTS1 antibody, Multiple tumor suppressor 1 antibody, p14 antibody, p14ARF antibody, P16 antibody, p16 INK4 antibody, p16 INK4a antibody, p16INK4 antibody, p16INK4a antibody, P19 antibody, TP16 antibody, P16-INK4A Antibody

Catalogue No.

FNab06064

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Description

P16-INK4A antibody: Rabbit Polyclonal antibody to P16-INK4A

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

Background

CDKN2A generates several transcript variants which differ in their first exons. At least three alternatively-spliced variants encoding distinct proteins have been reported, and two are related, named p16-INK4 and p14 respetively, sharing 50% identity. The third one is completely stuctually un-related, called p14 (ARF) or p19 (ARF) . FNab06064 reacted with p16 specifically. P16 plays an important role in regulating the cell cycle, and mutations in p16 increase the risk of developing a variety of cancers, notably melanoma.

Immunogen Information
Immunogen

cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)

Synonyms

ARF, CDKN2A, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16INK4, CDK4I, CDKN2, CDKN2A, CMM2, INK4, INK4a, MLM, MTS 1, MTS1, Multiple tumor suppressor 1, p14, p14ARF, P16, p16 INK4, p16 INK4a, p16INK4, p16INK4a, P19, TP16

Calculated MW

16kDa

Application
Specificity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF, IP, IHC, FC

Recommended dilution

WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500; IF: 1:20-1:200

Uniprot information
Gene Name

P16-INK4A

Uniprot ID

P42771

Images

anti- P16-INK4A antibody 1

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab06064 (P16-INK4A Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .


anti- P16-INK4A antibody 1

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06064 (P16 antibody) at dilution of 1:1000

Current product's manual: Manual

Protocol may be updated. Please feel free to contact Finetest Team to acquire the latest version.

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Hotline

027-87384275
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