Products
OLR1 antibody
- Product Name
- OLR1 antibody
- Catalogue No.
- FNab05990
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- oxidized low density lipoprotein (lectin-like) receptor 1
- Alternative Names
- CLEC8A antibody, hLOX 1 antibody, Lectin like oxLDL receptor 1 antibody, LOX 1 antibody, LOX1 antibody, OLR1 antibody, Ox LDL receptor 1 antibody, SCARE1 antibody
- UniProt ID
- P78380
- Observed MW
- 26 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab05990(OLR1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab05990( OLR1 Antibody) at dilution of 1:200
- Background
- This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
